Product Description: 
FOXO4-DRI is a modified D-retro-inverso peptide designed to interfere with the interaction between the FOXO4 transcription factor and p53 — a key survival mechanism used by senescent cells to evade apoptosis. By disrupting this interaction, FOXO4-DRI has emerged as one of the most studied senolytic compounds in aging biology research.
Current research has explored FOXO4-DRI in the following contexts: targeted clearance of senescent cells via apoptosis induction, FOXO4-p53 protein interaction disruption mechanisms, cellular aging and senescence biology, tissue rejuvenation following senescent cell accumulation, and healthspan and lifespan extension models in preclinical research.
 
Why Researchers Are Watching FOXO4-DRI 
Senescent cells — cells that have stopped dividing but resist death — accumulate with age and drive chronic inflammation and tissue dysfunction. FOXO4-DRI represents one of the most targeted approaches to senolytic research currently available, making it a cornerstone compound for serious longevity researchers.
 
Specifications: 10mg | Lyophilized powder | Purity ≥98% | Store at 2–8°C
 
For Research Use Only. Not intended for human or veterinary use.