Product Description:
MOTS-C (Mitochondrial Open Reading Frame of the Twelve S rRNA-c) is a mitochondria-derived peptide encoded within the mitochondrial genome — making it unique among research peptides. It functions as a mitochondrial signal that travels to the nucleus to regulate gene expression involved in metabolic homeostasis, stress response, and aging.
 
Current research has explored MOTS-C in the following contexts: mitochondrial-nuclear communication and retrograde signaling, insulin sensitivity and glucose metabolism regulation, exercise mimetic effects and metabolic flexibility, longevity and healthspan extension in aging models, obesity and metabolic disease research, and stress response and cellular homeostasis.
 
Why Researchers Are Watching MOTS-C 
MOTS-C represents a relatively new frontier in peptide research — mitochondria-derived peptides that regulate whole-body metabolism. Its potential as an exercise mimetic and metabolic regulator has made it one of the most talked-about compounds in the longevity and biohacking research community heading into 2026 and beyond.
 
Specifications: 10mg | Lyophilized powder | Purity ≥98% | Store at 2–8°C
 
For Research Use Only. Not intended for human or veterinary use.